Logix is a project I worked on back around 2004. Unfortunately it is entirely dormant right now, and personally I have no plans to resurrect it.
It is a front-end to Python that allows what I was then calling "Multi-language Programming". That is, you can easily create new languages, and use multiple languages freely in a single program.
It supports extensible syntax, true procedural macros and code-quoting as in Lisp, and "language inheritance" (creating new languages by extending existing ones).
It's pretty cool, if I do say so myself, and it would be great to see it picked up by someone.
There is a decent tutorial in the doc directory.
Logix is released under the GPL 2.