SigProfilerTopography allows evaluating the effect of chromatin organization, histone modifications, transcription factor binding, DNA replication, and DNA transcription on the activities of different mutational processes. SigProfilerTopography elucidates the unique topographical characteristics of mutational signatures.
bioinformatics
somatic-variants
cancer-genomics
mutation-analysis
mutational-signatures
mutation-topography
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Updated
May 18, 2024 - Python