regenerated-docs

derived/Antiphospholipid_Syndrome.html

@@ -86,6 +86,9 @@
  <th>
  description
  </th>
+ <th>
+ evidence
+ </th>
  </tr>
  <tr>
  <td>
@@ -94,6 +97,9 @@
  <td>
  occurs in the absence of any other related disease
  </td>
+ <td>
+ TRUNCATED
+ </td>
  </tr>
  <tr>
  <td>
@@ -102,6 +108,9 @@
  <td>
  occurs with other autoimmune diseases, such as systemic lupus erythematosus
  </td>
+ <td>
+ TRUNCATED
+ </td>
  </tr>
  <tr>
  <td>
@@ -110,6 +119,9 @@
  <td>
  individuals with antiphospholipid antibodies but no clinical symptoms
  </td>
+ <td>
+ TRUNCATED
+ </td>
  </tr>
  </table>
  </div>

derived/Antiphospholipid_Syndrome.yml

@@ -7,10 +7,57 @@ parents:
 has_subtypes:
  - name: Primary APS
  description: occurs in the absence of any other related disease
+ evidence:
+ - reference: PMID:16338214
+ supports: SUPPORT
+ snippet: the condition can exist on its own. APS appears to represent a clinical spectrum, both in terms of APS features and the presence of other autoimmune conditions. The clinical and serological characteristics of 'primary' APS (PAPS) are similar to those of secondary APS, although the clinical features are more commonly recognised in the presence of another autoimmune or inflammatory condition.
+ explanation: The passage supports the statement by indicating that APS can exist on its own without other related diseases, defining it as primary APS (PAPS).
+ - reference: PMID:27550302
+ supports: SUPPORT
+ snippet: APS can be isolated (primary APS) or associated with other autoimmune diseases.
+ explanation: This snippet reinforces that APS can exist independently as primary APS.
+ - reference: PMID:30419590
+ supports: SUPPORT
+ snippet: APS is classified as primary (PAPS) or secondary (SAPS) when it co-exists with another autoimmune disease.
+ explanation: Primary APS is explicitly defined as APS occurring without other related diseases (as opposed to secondary APS).
+ - reference: PMID:35042376
+ supports: SUPPORT
+ snippet: APS is classified as primary (PAPS) or secondary (SAPS) when it co-exists with another autoimmune disease.
+ explanation: The classification into primary APS supports the statement that it occurs in the absence of other related diseases.
  - name: Secondary APS
  description: occurs with other autoimmune diseases, such as systemic lupus erythematosus
+ evidence:
+ - reference: PMID:11014973
+ supports: SUPPORT
+ snippet: APS may be associated with another autoimmune disease (secondary APS), particularly systemic lupus erythematosus (SLE).
+ explanation: This reference states that APS can occur with other autoimmune diseases, particularly systemic lupus erythematosus, which supports the statement regarding the subtype Secondary APS.
+ - reference: PMID:15507265
+ supports: SUPPORT
+ snippet: Primary utilized when there is no associated disorder, secondary with an associated autoimmune disorder such as systemic lupus erythematosus (SLE).
+ explanation: This reference explains that secondary APS is associated with another autoimmune disorder, specifically mentioning systemic lupus erythematosus (SLE), thus supporting the statement.
+ - reference: PMID:19593144
+ supports: SUPPORT
+ snippet: Although originally described in the context of systemic lupus erythematosus, antiphospholipid syndrome was then recognized as a primary antiphospholipid syndrome without any underlying autoimmune disease in almost half of the cases.
+ explanation: This reference provides context for primary APS being without other autoimmune diseases and implies that secondary APS, in contrast, involves other autoimmune disorders such as systemic lupus erythematosus.
+ - reference: PMID:35896399
+ supports: SUPPORT
+ snippet: Systemic lupus erythematosus (SLE) and secondary anti-phospholipid syndrome (APS II) can cause increased morbidity and mortality of the fetus.
+ explanation: This article mentions secondary antiphospholipid syndrome in conjunction with systemic lupus erythematosus, supporting the existence of Secondary APS as a subtype of APS.
+ - reference: PMID:10866096
+ supports: SUPPORT
+ snippet: We retrospectively studied patients with APS and systemic lupus erythematosus (SLE)...39 patients had primary antiphospholipid syndrome (PAPS) and 69 secondary antiphospholipid syndrome (SAPS).
+ explanation: This article gives data on secondary APS occurring along with systemic lupus erythematosus, thus supporting the statement about the existence of the Secondary APS subtype.
+ - reference: PMID:26939208
+ supports: SUPPORT
+ snippet: The antiphospholipid syndrome (APS) is one of the most encountered autoimmunities in systemic lupus erythematosus (SLE) patients.
+ explanation: This article states that APS is common in SLE patients, indicating the close relationship between APS and SLE and supporting the subtype of Secondary APS.
  - name: Asymptomatic APS
  description: individuals with antiphospholipid antibodies but no clinical symptoms
+ evidence:
+ - reference: PMID:17145604
+ supports: SUPPORT
+ snippet: Antiphospholipid antibodies (aPL) and antiphospholipid syndrome (APS) are increasingly being recognized in children. Transient non-pathogenic aPL are often seen after childhood infections, while thrombotic events seem rare in those with true aPL.
+ explanation: The reference supports the existence of individuals with antiphospholipid antibodies but no clinical symptoms, which align with the description of Asymptomatic APS.
 prevalence:
  - subtype: Primary APS
  population: Global