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add author and IC ref
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menon-karthik committed Jun 27, 2024
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Expand Up @@ -16,9 +16,11 @@ authors:
- name: Martin R. Pfaller
affiliation: 1
equal-contrib: true
- name: Kaitlin E. Harold
affiliation: 1
- name: Jonathan Pham
affiliation: 1
- name: Kaitlin E. Harold
- name: Aekaansh Verma
affiliation: 1
- name: Dave Parker
affiliation: 1
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In particular, the C++ interface has been succesfully coupled with high-fidelity multi-physics solvers `svSolver` and `svFSI`, which are part of the widely used `Simvascular` open-source software project for cardiovascular biomechanics simulations [@Updegrove2017;@Zhu2022].
`svZeroDSolver` has also been integrated into the graphical user interface of the `Simvascular` project.
This allows users to leverage the functionality in `Simvascular` to generate three-dimensional patient-specific anatomical models from medical images, and subsequently perform patient-specific zero-dimensional simulations of blood flow by automatically converting the three-dimensional anatomy into a zero-dimensional model [@pfaller22].
Using this pipeline, previous work has demonstrated improved convergence of three-dimensional simulations when using corresponding zero-dimensional simulation results as initial conditions [@pfaller21].

In addition, the `svZeroDCalibrator` application within `svZeroDSolver` includes functionality to improve the accuracy of zero-dimensional models by optimizing the parameters of blood vessels to recapitulate observed hemodynamics from measurements or high-fidelity simulations.
This allows users to build more accurate zero-dimensional models than those typically based on purely the anatomy of the vascular region of interest [@richter2024bayesian].
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# Acknowledgments

This work was supported by ???. Previous contributions to the software by Dr. Aekaansh Verma are acknowledged.
This work was supported by NSF grant ???.

# References

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