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Antimalarial Drug Resistance Simulation

This repository contains the input data and source code for an individual-based simulation that was a part of the scientific publication titled "Preventing Antimalarial Drug Resistance with Triple Artemisinin-Based Combination Therapies" published in Nature Communications in July 2023.

Authors: Tran Dang Nguyen, Bo Gao, Chanaki Amaratunga, Mehul Dhorda, Thu Nguyen-Anh Tran, Nicholas J. White, Arjen M. Dondorp, Maciej F. Boni, Ricardo Aguas

DOI: 10.1038/s41467-023-39914-3

Repository Structure

  • source_code/: Contains the source code for the individual-based simulation.
  • input/: Includes the input data required for running the simulation.

How to Use

To reproduce or further explore the simulation described in the publication, follow these steps:

  1. Clone the repository to your local machine:

    git clone https://github.com/bonilab/malariaibm-TACT-2023.git
  2. The README file in the source_code/ directory contains detailed information on how to build and run the simulation. If you require additional assistance or have questions, please feel free to contact the corresponding author. Execute the simulation code using your preferred environment or tools. Be sure to refer to the publication and any additional documentation for specific instructions on running the simulation.

Citation

If you use or refer to the results, code, or data from this repository in your research or work, please cite the original publication:

Nguyen, T.D., Gao, B., Amaratunga, C. et al. Preventing antimalarial drug resistance with triple artemisinin-based combination therapies. Nat Commun 14, 4568 (2023). https://doi.org/10.1038/s41467-023-39914-3

For questions or inquiries, please contact the corresponding author or create an issue in this repository.

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