Daphne dev

DESCRIPTION

@@ -19,6 +19,7 @@ Imports:
  stringr
 Depends: 
  R (>= 2.10)
+Config/testthat/edition: 3
 Suggests: 
  knitr,
  rmarkdown,

R/parse_vcf.R

@@ -6,45 +6,122 @@
 #' @param type Which input format will be generated. Options: ncd1, ncd2.
 #' @return Returns a data table object with columns CHR POS REF ALT tx_1 tn_1 (if type is ncd1) or CHR POS REF ALT tx_1 tn_1 tx_2 tn_2 (if type is ncd2)
 #' @export
-#' @examples parse_vcf(infile=system.file(package="balselr", "example.vcf"), n0=108, type="ncd1")
-#' @examples parse_vcf(infile=system.file(package="balselr", "example.vcf"), n0=108, n1=1, type="ncd2")
-#' @param verbose Logical. Printed updates. Default is T.
-
-# to do: test that outputs of both commands in the examples have the same values for tx_1 and tn_1
-parse_vcf <- function(infile = NULL,
- n0 = NULL,
- n1 = NULL,
- type = NULL,
- verbose=F) {
-
- assertthat::assert_that(file.exists(infile),
- msg = glue::glue("VCF file {infile} does not exist.\n"))
- #to do: check that n0 and n1 meet requirements outlined above.
- #to do: check that vcf file has at least the number of individuals provided in n0+n1 (i.e., if users says n0=10, n1=1 but vcf only has 8 individuals, this should return an error as early as possible)
- type <- tolower(type)
- assertthat::assert_that(type %in% c("ncd1", "ncd2"), msg = "ncd_type must be either ncd1 or ncd2.\n")
- if (type == "ncd2") {
- assertthat::assert_that(is.null(n1) == FALSE, msg = "n1 cannot be 'NULL'. NCD2 requires an outgroup at least one individual as an outgroup.")
+#'
+#' @examples parse_vcf(infile="inst/example.vcf", outfile="inst/example_parse_ncd1.out", n0=108, type="ncd1")
+#'parse_vcf(infile="inst/example.vcf",n0=108, n1=1, type="ncd2", outfile="example_parse_ncd2.out")
+
+parse_vcf <-
+ function(infile = "*.vcf",
+ outfile = NULL,
+ n0= NULL,
+ n1= NULL,
+ type = NULL,
+ fold = T,
+ intern = T,
+ verbose = T) {
+ tictoc::tic("Total runtime")
+ assertthat::assert_that(file.exists(infile),
+ msg = glue::glue("VCF file {infile} does not exist.\n")
+ )
+ assertthat::assert_that(is.numeric(n0)
+ )
+ format_type <- function(type) {
+ incorrect_types_ncd1 <- c("ncd1", "ned1", "ncd_1", "ned_1")
+ incorrect_types_ncd2 <- c("ncd2", "ned2", "ncd_2", "ned_2")
+
+ type <- tolower(type)
+ if (type %in% incorrect_types_ncd1) {
+ type <- "ncd1"
+ } else if (type %in% incorrect_types_ncd2) {
+ type <- "ncd2"
+ }
+
+ return(type)
+
  }
- inp <- read_vcf(x = infile)
- nind<-c(n0,n1)
- index.col <- which(colnames(inp) == "FORMAT") + 1
- if (type == "ncd2") {
- res <-
- .vcf_ncd2(
- x = inp,
- nind = nind,
- index.col = index.col,
- verbose = verbose
- )
- } else if (type == "ncd1") {
- res <-
- .vcf_ncd1(
- x = inp,
- nind = nind,
- index.col = index.col,
- verbose = verbose
- )
+ if (is.null(type)) {
+ print("You must choose either 'ncd1' or 'ncd2'")
+ return(NULL)
  }
- return(res)
-}
+ # Index No. of the individual to use as ``ancestral'' sequence
+ if (fold == F & type == "ncd2") {
+ outseq <- (index.col) + (sum(nind) - 1)
+ if (verbose == T) {
+ cat(
+ glue::glue(
+ "You asked for the unfolded version. You need a third species. I will use column {outseq} for this."
+ ),
+ "\n"
+ )
+ }
+ }else if (type == "ncd2"){
+ assertthat::assert_that(is.null(n1)==FALSE, msg="n1 cannot be NULL. NCD2 requires an outgroup.")
+ }
+ else if (type == "ncd1") {
+ assertthat::assert_that(fold == T, msg = "Only the folded option is available when Ancestral/Derived states are unknown.\n")
+ }
+ #
+ if (is.null(outfile)) {
+ outfile = outfile_path(glue::glue("{infile}"))
+ if (verbose == T) {
+ cat(
+ glue::glue(
+ "No outfile provided. Will write this into tmp file {outfile}_{type}.out"
+ ),
+ "\n"
+ )
+ }
+ }else{
+ outfile <- glue::glue("{outfile}_{type}.out")
+ }
+
+ nind<-c(n0,n1)
+ pref <- gsub(".vcf", "", infile)
+ inp <- read_vcf(x = infile, only.bi = T)
+
+ index.col <- which(colnames(inp) == "FORMAT") + 1
+ if (verbose == T) {
+ cat(
+ glue::glue(
+ "First genotype column is {index.col}"
+ ), "\n"
+ )
+ }
+ if (verbose == T) {
+ cat(
+ glue::glue("Creating input file for {type} from {infile}..."),
+ "\n"
+ )
+ }
+
+
+ #
+ if (type == "ncd2") {
+ res <-
+ .vcf_ncd2(
+ x = inp,
+ outfile = outfile,
+ nind = nind,
+ index.col = index.col,
+ fold = fold,
+ verbose = verbose
+ )
+ } else if (type == "ncd1") {
+ res <-
+ .vcf_ncd1(
+ x = inp,
+ outfile = outfile,
+ nind = nind,
+ index.col = index.col,
+ verbose = verbose
+ )
+ }
+ if (verbose == T) {
+ cat(
+ glue::glue("Finished making input file for {type}. File written to: {outfile}"),
+ "\n"
+ )
+ tictoc::toc()
+ } else {
+ cat(glue::glue("File written to: {outfile}"), "\n")
+ }

R/read_vcf.R

@@ -12,6 +12,5 @@ read_vcf <- function(x = "inst/example.vcf") {
  inp <- data.table::fread(x, skip = "##", header = T)
  data.table::setnames(inp, "#CHROM", "CHR")
  #inp <-
- inp[REF %in% c("A", "C", "T", "G")][ALT %in% c("A", "C", "T", "G")]
- #return(inp)
+ inp[REF %in% c("A", "C", "T", "G")][ALT %in% c("A", "C", "T", "G")]
 }

data-raw/DATASET.R

@@ -1,3 +0,0 @@
-## code to prepare `DATASET` dataset goes here
-
-usethis::use_data(DATASET, overwrite = TRUE)

tests/testthat.R

@@ -5,8 +5,3 @@
 # Learn more about the roles of various files in:
 # * https://r-pkgs.org/tests.html
 # * https://testthat.r-lib.org/reference/test_package.html#special-files
-
-library(testthat)
-library(balselr)
-
-test_check("balselr")