To install:
if (!require(devtools)) {
install.packages("devtools")
}
devtools::install_github("ari7cr/iCCL1")
library(iCCL1)
Flowchart:
Functions:
-
predictdimensions(SeuratObject) -> gives back an estimated Dimension to run clustering for
-
iCCL(SeuratObject, x, y)
Basically 1-command, multi-dimension UMAP Seurat clustering for your SeuratObject from your range of choice: x (>3) to y.
This Package is currently undergoing maintenace for improving
Planned for iCCL2: t-SNE adaption
Long-Term goals: Clustering Scores (ideas and participation very much appreciated!)
This package builds upon Seurat methods: https://www.biorxiv.org/content/10.1101/2020.10.12.335331v1
The method which predictdimension() builds on was developed by Harvard Chan Bioinformatics Core: https://bioinformatics.sph.harvard.edu/
Arian Abbasi
[email protected]
University of Cologne