CACIMAR: cross-species analysis of cell identities, markers and regulations using single-cell sequencing profiles

CACIMAR has the following 4 main functions:

• Identify all cell-type specific markers in each species

• Identify species-specific or evolutionally conserved markers

• Identify conserved intracellular regulations (gene regulatory networks)

• Identify conserved intercellular interactions (cell-cell communications)

Installation

Install CACIMAR from github, run:

# install.packages("devtools")
devtools::install_github("jiang-junyao/CACIMAR")

News

Version1.0.0: First version of CACIMAR was published!

Tutorial

Using CACIMAR to analyze retina scRNA-seq data from mouse and zebrafish

Citation

Preprint: CACIMAR Cross-species Analysis of Cell Identities, Markers, Regulations and Interactions Using Single-cell RNA Sequencing Data(https://www.biorxiv.org/content/10.1101/2024.01.23.576964v1)