INDEXEVENT is a package for adjusting association statistics for index event bias.
To install within R:
devtools::install_github("DudbridgeLab/indexevent")
To see a toy example:
help(testData)
For more details on usage:
help(indexevent)
This software has been tested in R 3.3.1 under Windows 7, and R 3.4.1 under CentOS Linux. For most applications it will run on a standard desktop PC.
Dudbridge, F., Allen, R.J., Sheehan, N.A. et al. Adjustment for index event bias in genome-wide association studies of subsequent events. Nat Commun 10, 1561 (2019). https://doi.org/10.1038/s41467-019-09381-w