diff --git a/extensions/mybatis/runtime/pom.xml b/extensions/mybatis/runtime/pom.xml
index d38c3c8250f0e3..ee55066abf1e3a 100644
--- a/extensions/mybatis/runtime/pom.xml
+++ b/extensions/mybatis/runtime/pom.xml
@@ -27,6 +27,10 @@
             <groupId>org.mybatis</groupId>
             <artifactId>mybatis</artifactId>
         </dependency>
+        <dependency>
+            <groupId>org.graalvm.nativeimage</groupId>
+            <artifactId>svm</artifactId>
+        </dependency>
     </dependencies>
 
     <build>
diff --git a/extensions/mybatis/runtime/src/main/java/io/quarkus/mybatis/runtime/graal/DefineClassHelperSubstitution.java b/extensions/mybatis/runtime/src/main/java/io/quarkus/mybatis/runtime/graal/DefineClassHelperSubstitution.java
new file mode 100644
index 00000000000000..382444d04850d8
--- /dev/null
+++ b/extensions/mybatis/runtime/src/main/java/io/quarkus/mybatis/runtime/graal/DefineClassHelperSubstitution.java
@@ -0,0 +1,25 @@
+package io.quarkus.mybatis.runtime.graal;
+
+import java.lang.invoke.MethodHandles;
+
+import org.apache.ibatis.javassist.CannotCompileException;
+import org.apache.ibatis.javassist.util.proxy.DefineClassHelper;
+
+import com.oracle.svm.core.annotate.Substitute;
+import com.oracle.svm.core.annotate.TargetClass;
+import com.oracle.svm.core.jdk.JDK8OrEarlier;
+
+@TargetClass(value = DefineClassHelper.class, onlyWith = JDK8OrEarlier.class)
+final public class DefineClassHelperSubstitution {
+
+    @Substitute
+    public static Class<?> toClass(MethodHandles.Lookup lookup, byte[] bcode) throws CannotCompileException {
+        throw new CannotCompileException("Not support");
+    }
+
+    @Substitute
+    static Class<?> toPublicClass(String className, byte[] bcode) throws CannotCompileException {
+        throw new CannotCompileException("Not support");
+    }
+
+}