Skip to content
New issue

Have a question about this project? Sign up for a free GitHub account to open an issue and contact its maintainers and the community.

By clicking “Sign up for GitHub”, you agree to our terms of service and privacy statement. We’ll occasionally send you account related emails.

Already on GitHub? Sign in to your account

Questions about the number of microRNAs #1

Closed
YangXinyan opened this issue Aug 28, 2023 · 1 comment
Closed

Questions about the number of microRNAs #1

YangXinyan opened this issue Aug 28, 2023 · 1 comment

Comments

@YangXinyan
Copy link

To developers

miRTalk is an interesting work, but I have some doubts. What do you think of the fact that it is almost difficult to detect micro RNA in the 10X data. According to 10X genomic, almost no mature micro RNA can be detected in the data (Ref 1-2). As in the Demo data, only 60+ micro RNAs were detected in the end.

Ref 1-2:
https://kb.10xgenomics.com/hc/en-us/articles/360002004271-Is-it-possible-to-capture-microRNAs-in-the-Gene-Expression-assays-
https://kb.10xgenomics.com/hc/en-us/articles/217261666-What-types-of-RNA-can-be-detected-

with regards,
Xinyan Yang

@multitalk
Copy link
Owner

For 10X Genomics data, the miRNAs refer to the pri-miRNA transcripts. For the STRS data(https://doi.org/10.1038/s41587-022-01517-6), the miRNAs refer to the mature miRNA transcripts.

Sign up for free to join this conversation on GitHub. Already have an account? Sign in to comment
Labels
None yet
Projects
None yet
Development

No branches or pull requests

2 participants