Questions about the number of microRNAs

[YangXinyan]

To developers

miRTalk is an interesting work, but I have some doubts. What do you think of the fact that it is almost difficult to detect micro RNA in the 10X data. According to 10X genomic, almost no mature micro RNA can be detected in the data (Ref 1-2). As in the Demo data, only 60+ micro RNAs were detected in the end.

Ref 1-2:
https://kb.10xgenomics.com/hc/en-us/articles/360002004271-Is-it-possible-to-capture-microRNAs-in-the-Gene-Expression-assays-
https://kb.10xgenomics.com/hc/en-us/articles/217261666-What-types-of-RNA-can-be-detected-

with regards,
Xinyan Yang

[multitalk]

For 10X Genomics data, the miRNAs refer to the pri-miRNA transcripts. For the STRS data(https://doi.org/10.1038/s41587-022-01517-6), the miRNAs refer to the mature miRNA transcripts.