Skip to content
New issue

Have a question about this project? Sign up for a free GitHub account to open an issue and contact its maintainers and the community.

By clicking “Sign up for GitHub”, you agree to our terms of service and privacy statement. We’ll occasionally send you account related emails.

Already on GitHub? Sign in to your account

question about LCB determination #50

Open
0xaf1f opened this issue Aug 3, 2023 · 0 comments
Open

question about LCB determination #50

0xaf1f opened this issue Aug 3, 2023 · 0 comments

Comments

@0xaf1f
Copy link

0xaf1f commented Aug 3, 2023

I was interested in how the LCBs called by SibeliaZ change as I include more genomes, so to start, I ran it with two ~4.5Mb genomes that differed only by a single ~10kb inversion that I introduced. I expected to see something like 3 LCBs since the sequences are otherwise identical, but I was getting around 2100. I can't find anything in the algorithm description in your paper to explain this. There should only be bubbles in the vicinity of the inversion that I introduced, but nowhere else. Is the large number of LCBs for these near-identical genomes expected behavior, and how?

Sign up for free to join this conversation on GitHub. Already have an account? Sign in to comment
Labels
None yet
Projects
None yet
Development

No branches or pull requests

1 participant