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Usage of cobra #25

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quliping opened this issue Feb 26, 2024 · 2 comments
Open

Usage of cobra #25

quliping opened this issue Feb 26, 2024 · 2 comments

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@quliping
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Cobra is an interesting software, but I have some questions. Is the input data must be viral metagenome data? I'm not sure if cobra could works for common metagenome data and will cobra produce some bacteria or archaea MAGs? Thanks.

@linxingchen
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Hi, thanks for your interest in COBRA. Could you please refer to Issue#22 regarding the usage of COBRA on whole metagenomes? Let me know if anything stated therein is unclear.

Best,
LINXING

@linxingchen
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Technically, you could use COBRA before binning, this step will make some of your contigs/scaffolds longer, but the issue is you have to rerun the mapping for a new sequencing coverage profile.

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