From 1067b891097a0d45af692b2f02edb98e67565e2b Mon Sep 17 00:00:00 2001 From: "Anna M. Wilke" Date: Mon, 6 Jun 2022 09:49:04 -0400 Subject: [PATCH] adding recent adaptive trial example --- adaptive/adaptive.Rmd | 2 +- adaptive/adaptive.html | 7 ++++++- 2 files changed, 7 insertions(+), 2 deletions(-) diff --git a/adaptive/adaptive.Rmd b/adaptive/adaptive.Rmd index 0222212..25eac21 100644 --- a/adaptive/adaptive.Rmd +++ b/adaptive/adaptive.Rmd @@ -80,7 +80,7 @@ The use of adaptive designs introduces additional decisions, which ideally shoul == Many of the applications to date have taken place in commercial settings, such as website design for high-volume e-commerce, or in settings such as on-line fundraising. Relatively few applications have been written up in detail for a scholarly audience. Surprisingly rare are applications in biomedical research. As Villar et al. (2015, p.200) note, “Despite this apparent near-perfect fit between a real-world problem and a mathematical theory, the MABP has yet to be applied to an actual clinical trial.” -Putting aside the use of multi-arm bandit approaches, the use of adaptive trials is gradually winning acceptance in biomedical research. For details, see Chin (2016). +Putting aside the use of multi-arm bandit approaches, the use of adaptive trials is gradually winning acceptance in biomedical research. See Chin (2016) for details and [https://www.remapcap.org/](https://www.remapcap.org/) for a prominent example. 10. What other considerations should inform the decision to use adaptive design? == diff --git a/adaptive/adaptive.html b/adaptive/adaptive.html index 1f35b54..9c1a815 100644 --- a/adaptive/adaptive.html +++ b/adaptive/adaptive.html @@ -266,6 +266,7 @@ +