-
Notifications
You must be signed in to change notification settings - Fork 73
New issue
Have a question about this project? Sign up for a free GitHub account to open an issue and contact its maintainers and the community.
By clicking “Sign up for GitHub”, you agree to our terms of service and privacy statement. We’ll occasionally send you account related emails.
Already on GitHub? Sign in to your account
RCTD method's cell type weights doesn't sum to 1 #193
Comments
Don't know enough to know exactly how to interpret differences in weight sums, but just note that this is mentioned in their vignette where they run the |
Sign up for free
to join this conversation on GitHub.
Already have an account?
Sign in to comment
Hi,
I'm using the RCTD method for cell type deconvolution. When I apply RCTD in both full and doublet modes, the results, which include the cell type weights for each pixel, don't sum up to 1. I thought these weights represent the cell type proportions for each spot (pixel), and so, shouldn't they add up to 1 for each pixel?
For further clarification, I have attached a screenshot of the output I obtained using the same codes and data provided by the vignette. In the below output, we can see that the proportions don't add to 1. I hope you can help me clarify this matter.
The text was updated successfully, but these errors were encountered: