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test-par.txt
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test-par.txt
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Parental composition of sequence SCH2
10 20 30 40 50 60 70 80 90 100 110 120
SCH2 MAADGYLPDWLEDNLSEGIREWWDLKPGAPKPKANQQKQDDGRGLVLPGYKYLGPFNGLDKGEPVNAADAAALEHDKAYDQQLKAGDNPYLRYNHADAEFQERLQEDTSFGGNLGRAVFQ
AAV2
AAV6 ........................................................................................................................
AAV8
AAV9
130 140 150 160 170 180 190 200 210 220 230 240
SCH2 AKKRVLEPLGLVEEAAKTAPGKKRPVEQSPQEPDSSAGIGKSGAQPAKKRLNFGQTGDTESVPDPQPIGEPPAAPSGVGSLTMASGGGAPVADNNEGADGVGSSSGNWHCDSQWLGDRVI
AAV2
AAV6 ........
AAV8
AAV9 ...................................................................................................................
250 260 270 280 290 300 310 320 330 340 350 360
SCH2 TTSTRTWALPTYNNHLYKQISNSTSGGSSNDNAYFGYSTPWGYFDFNRFHCHFSPRDWQRLINNNWGFRPKRLSFKLFNIQVKEVTQNEGTKTIANNLTSTIQVFTDSDYQLPYVLGSAH
AAV2
AAV8 ...........................................................................
AAV9 ......................................................................... ..................
370 380 390 400 410 420 430 440 450 460 470 480
SCH2 EGCLPPFPADVFMIPQYGYLTLNDGSQAVGRSSFYCLEYFPSQMLRTGNNFQFSYTFEDVPFHSSYAHSQSLDRLMNPLIDQYLYYLSRTNTPSGTTTQSRLQFSQAGASDIRDQSRNWL
AAV2 ....................................................................
AAV9 .......................................................
490 500 510 520 530 540 550 560 570 580 590 600
SCH2 PGPCYRQQRVSKTSADNNNSEYSWTGATKYHLNGRDSLVNPGPAMASHKDDEEKFFPQSGVLIFGKQGSEKTNVDIEKVMITDEEEIRTTNPVATEQYGSVSTNLQRGNRQAATADVNTQ
AAV2 ........................................................................................................................
AAV9
610 620 630 640 650 660 670 680 690 700 710 720
SCH2 GVLPGMVWQDRDVYLQGPIWAKIPHTDGNFHPSPLMGGFGMKHPPPQILIKNTPVPADPPTAFNKDKLNSFITQYSTGQVSVEIEWELQKENSKRWNPEIQYTSNYYKSNNVEFAVNTEG
AAV2 ............................
AAV9 ......................................................................................................................
730
SCH2 VYSEPRPIGTRYLTRNL
AAV9 .................
Parental composition of sequence SCH9
10 20 30 40 50 60 70 80 90 100 110 120
SCH9 MAADGYLPDWLEDNLSEGIREWWDLKPGAPKPKANQQKQDDGRGLVLPGYKYLGPFNGLDKGEPVNAADAAALEHDKAYDQQLKAGDNPYLRYNHADAEFQERLQEDTSFGGNLGRAVFQ
AAV2
AAV6 ........................................................................................................................
AAV8
AAV9
130 140 150 160 170 180 190 200 210 220 230 240
SCH9 AKKRVLEPLGLVEEAAKTAPGKKRPVEQSPQEPDSSAGIGKSGAQPAKKRLNFGQTGDTESVPDPQPIGEPPAAPSGVGSLTMASGGGAPVADNNEGADGVGSSSGNWHCDSQWLGDRVI
AAV2
AAV6 ........
AAV8
AAV9 ...................................................................................................................
250 260 270 280 290 300 310 320 330 340 350 360
SCH9 TTSTRTWALPTYNNHLYKQISNSTSGGSSNDNAYFGYSTPWGYFDFNRFHCHFSPRDWQRLINNNWGFRPKRLSFKLFNIQVKEVTQNEGTKTIANNLTSTIQVFTDSDYQLPYVLGSAH
AAV2
AAV8 ...........................................................................
AAV9 ......................................................................... ..................
370 380 390 400 410 420 430 440 450 460 470 480
SCH9 EGCLPPFPADVFMIPQYGYLTLNDGSQAVGRSSFYCLEYFPSQMLRTGNNFQFSYEFENVPFHSSYAHSQSLDRLMNPLIDQYLYYLSKTINGSGQNQQTLKFSVAGPSNMAVQGRNWLP
AAV2 .....
AAV9 .....................................................................................................................
490 500 510 520 530 540 550 560 570 580 590 600
SCH9 GPCYRQQRVSKTSADNNNSEYSWTGATKYHLNGRDSLVNPGPAMASHKDDEEKFFPQSGVLIFGKQGSEKTNVDIEKVMITDEEEIRTTNPVATEQYGSVSTNLQRGNRQAATADVNTQG
AAV2 ........................................................................................................................
AAV9
610 620 630 640 650 660 670 680 690 700 710 720
SCH9 VLPGMVWQDRDVYLQGPIWAKIPHTDGNFHPSPLMGGFGMKHPPPQILIKNTPVPADPPTAFNKDKLNSFITQYSTGQVSVEIEWELQKENSKRWNPEIQYTSNYYKSNNVEFAVNTEGV
AAV2 ...........................
AAV9 .......................................................................................................................
730
SCH9 YSEPRPIGTRYLTRNL
AAV9 ................
Parental composition of sequence AAV-F
10 20 30 40 50 60 70 80 90 100 110 120
AAV-F MAADGYLPDWLEDNLSEGIREWWALKPGAPQPKANQQHQDNARGLVLPGYKYLGPGNGLDKGEPVNAADAAALEHDKAYDQQLKAGDNPYLKYNHADAEFQERLKEDTSFGGNLGRAVFQ
AAV9 ........................................................................................................................
130 140 150 160 170 180 190 200 210 220 230 240
AAV-F AKKRLLEPLGLVEEAAKTAPGKKRPVEQSPQEPDSSAGIGKSGAQPAKKRLNFGQTGDTESVPDPQPIGEPPAAPSGVGSLTMASGGGAPVADNNEGADGVGSSSGNWHCDSQWLGDRVI
AAV9 ........................................................................................................................
250 260 270 280 290 300 310 320 330 340 350 360
AAV-F TTSTRTWALPTYNNHLYKQISNSTSGGSSNDNAYFGYSTPWGYFDFNRFHCHFSPRDWQRLINNNWGFRPKRLNFKLFNIQVKEVTDNNGVKTIANNLTSTVQVFTDSDYQLPYVLGSAH
AAV9 ........................................................................................................................
370 380 390 400 410 420 430 440 450 460 470 480
AAV-F EGCLPPFPADVFMIPQYGYLTLNDGSQAVGRSSFYCLEYFPSQMLRTGNNFQFSYEFENVPFHSSYAHSQSLDRLMNPLIDQYLYYLSKTINGSGQNQQTLKFSVAGPSNMAVQGRNYIP
AAV9 ........................................................................................................................
490 500 510 520 530 540 550 560 570 580 590 600
AAV-F GPSYRQQRVSTTVTQNNNSEFAWPGASSWALNGRNSLMNPGPAMASHKEGEDRFFPLSGSLIFGKQGTGRDNVDADKVMITNEEEIKTTNPVATESYGQVATNHQSAQFVVGQSYAQAQT
AAV9 ............................................................................................................-------.....
610 620 630 640 650 660 670 680 690 700 710 720
AAV-F GWVQNQGILPGMVWQDRDVYLQGPIWAKIPHTDGNFHPSPLMGGFGMKHPPPQILIKNTPVPADPPTAFNKDKLNSFITQYSTGQVSVEIEWELQKENSKRWNPEIQYTSNYYKSNNVEF
AAV9 ........................................................................................................................
730 740
AAV-F AVNTEGVYSEPRPIGTRYLTRNL
AAV9 .......................
Parental composition of sequence AAV-DJ
10 20 30 40 50 60 70 80 90 100 110 120
AAV-DJ MAADGYLPDWLEDTLSEGIRQWWKLKPGPPPPKPAERHKDDSRGLVLPGYKYLGPFNGLDKGEPVNEADAAALEHDKAYDRQLDSGDNPYLKYNHADAEFQERLKEDTSFGGNLGRAVFQ
AAV2 ........................................................................................................................
AAV8
AAV9 ...................................
130 140 150 160 170 180 190 200 210 220 230 240
AAV-DJ AKKRLLEPLGLVEEAAKTAPGKKRPVEHSPVEPDSSSGTGKAGQQPARKRLNFGQTGDADSVPDPQPIGEPPAAPSGVGSLTMAAGGGAPMADNNEGADGVGNSSGNWHCDSTWMGDRVI
AAV2 .... ................................................... .................................
AAV8 .....................
AAV9 ........................... ........................ .....
250 260 270 280 290 300 310 320 330 340 350 360
AAV-DJ TTSTRTWALPTYNNHLYKQISNSTSGGSSNDNAYFGYSTPWGYFDFNRFHCHFSPRDWQRLINNNWGFRPKRLSFKLFNIQVKEVTQNEGTKTIANNLTSTIQVFTDSEYQLPYVLGSAH
AAV2 .....................
AAV8 .......................................................................................
AAV9 .........................................................................
370 380 390 400 410 420 430 440 450 460 470 480
AAV-DJ QGCLPPFPADVFMIPQYGYLTLNNGSQAVGRSSFYCLEYFPSQMLRTGNNFQFTYTFEDVPFHSSYAHSQSLDRLMNPLIDQYLYYLSRTQTTGGTTNTQTLGFSQGGPNTMANQAKNWL
AAV2 ...
AAV8 ................................................................................................A.......................
490 500 510 520 530 540 550 560 570 580 590 600
AAV-DJ PGPCYRQQRVSKTSADNNNSEYSWTGATKYHLNGRDSLVNPGPAMASHKDDEEKFFPQSGVLIFGKQGSEKTNVDIEKVMITDEEEIRTTNPVATEQYGSVSTNLQRGNRQAATADVNTQ
AAV2 ........................................................................................................................
AAV8 ...........
610 620 630 640 650 660 670 680 690 700 710 720
AAV-DJ GVLPGMVWQDRDVYLQGPIWAKIPHTDGHFHPSPLMGGFGLKHPPPQILIKNTPVPADPPTTFNQSKLNSFITQYSTGQVSVEIEWELQKENSKRWNPEIQYTSNYYKSTSVDFAVNTEG
AAV2 .........................................................
AAV8 ...........................................................................................
730
AAV-DJ VYSEPRPIGTRYLTRNL
AAV8 .................
Parental composition of sequence AAV-PHP.B
10 20 30 40 50 60 70 80 90 100 110 120
AAV-PHP.B MAADGYLPDWLEDNLSEGIREWWALKPGAPQPKANQQHQDNARGLVLPGYKYLGPGNGLDKGEPVNAADAAALEHDKAYDQQLKAGDNPYLKYNHADAEFQERLKEDTSFGGNLGRAVFQ
AAV9 ........................................................................................................................
130 140 150 160 170 180 190 200 210 220 230 240
AAV-PHP.B AKKRLLEPLGLVEEAAKTAPGKKRPVEQSPQEPDSSAGIGKSGAQPAKKRLNFGQTGDTESVPDPQPIGEPPAAPSGVGSLTMASGGGAPVADNNEGADGVGSSSGNWHCDSQWLGDRVI
AAV9 ........................................................................................................................
250 260 270 280 290 300 310 320 330 340 350 360
AAV-PHP.B TTSTRTWALPTYNNHLYKQISNSTSGGSSNDNAYFGYSTPWGYFDFNRFHCHFSPRDWQRLINNNWGFRPKRLNFKLFNIQVKEVTDNNGVKTIANNLTSTVQVFTDSDYQLPYVLGSAH
AAV9 ........................................................................................................................
370 380 390 400 410 420 430 440 450 460 470 480
AAV-PHP.B EGCLPPFPADVFMIPQYGYLTLNDGSQAVGRSSFYCLEYFPSQMLRTGNNFQFSYEFENVPFHSSYAHSQSLDRLMNPLIDQYLYYLSKTINGSGQNQQTLKFSVAGPSNMAVQGRNYIP
AAV9 ........................................................................................................................
490 500 510 520 530 540 550 560 570 580 590 600
AAV-PHP.B GPSYRQQRVSTTVTQNNNSEFAWPGASSWALNGRNSLMNPGPAMASHKEGEDRFFPLSGSLIFGKQGTGRDNVDADKVMITNEEEIKTTNPVATESYGQVATNHQSAQTLAVPFKAQAQT
AAV9 ............................................................................................................-------.....
610 620 630 640 650 660 670 680 690 700 710 720
AAV-PHP.B GWVQNQGILPGMVWQDRDVYLQGPIWAKIPHTDGNFHPSPLMGGFGMKHPPPQILIKNTPVPADPPTAFNKDKLNSFITQYSTGQVSVEIEWELQKENSKRWNPEIQYTSNYYKSNNVEF
AAV9 ........................................................................................................................
730 740
AAV-PHP.B AVNTEGVYSEPRPIGTRYLTRNL
AAV9 .......................
Parental composition of sequence AAV2.5T
10 20 30 40 50 60 70 80 90 100 110 120
AAV2.5T MAADGYLPDWLEDTLSEGIRQWWKLKPGPPPPKPAERHKDDSRGLVLPGYKYLGPFNGLDKGEPVNEADAAALEHDKAYDRQLDSGDNPYLKYNHADAEFQERLKEDTSFGGNLGRAVFQ
AAV2 ........................................................................................................................
AAV5 ....
130 140 150 160 170 180 190 200 210 220 230 240
AAV2.5T AKKRVLEPFGLVEEGAKTAPTGKRIDDHFPKRKKARTEEDSKPSTSSDAEAGPSGSQQLQIPAQPASSLGADTMSAGGGGPLGDNNQGADGVGNASGDWHCDSTWMGDRVVTKSTRTWVL
AAV2 ........
AAV5 ........................................................................................................................
250 260 270 280 290 300 310 320 330 340 350 360
AAV2.5T PSYNNHQYREIKSGSVDGSNANAYFGYSTPWGYFDFNRFHSHWSPRDWQRLINNYWGFRPRSLRVKIFNIQVKEVTVQDSTTTIANNLTSTVQVFTDDDYQLPYVVGNGTEGCLPAFPPQ
AAV5 ........................................................................................................................
370 380 390 400 410 420 430 440 450 460 470 480
AAV2.5T VFTLPQYGYATLNRDNTENPTERSSFFCLEYFPSKMLRTGNNFEFTYNFEEVPFHSSFAPSQNLFKLANPLVDQYLYRFVSTNNTGGVQFNKNLAGRYANTYKNWFPGPMGRTQGWNLGS
AAV5 ........................................................................................................................
490 500 510 520 530 540 550 560 570 580 590 600
AAV2.5T GVNRASVSAFATTNRMELEGASYQVPPQPNGMTNNLQGSNTYALENTMIFNSQPANPGTTATYLEGNMLITSESETQPVNRVAYNVGGQMATNNQSSTTAPTTGTYNLQEIVPGSVWMER
AAV5 .....................................................................................................A..................
610 620 630 640 650 660 670 680 690 700 710 720
AAV2.5T DVYLQGPIWAKIPETGAHFHPSPAMGGFGLKHPPPMMLIKNTPVPGNITSFSDVPVSSFITQYSTGQVTVEMEWELKKENSKRWNPEIQYTNNYNDPQFVDFAPDSTGEYRTTRPIGTRY
AAV5 ........................................................................................................................
AAV2.5T LTRPL
AAV5 .....
Parental composition of sequence 7m8
10 20 30 40 50 60 70 80 90 100 110 120
7m8 MAADGYLPDWLEDTLSEGIRQWWKLKPGPPPPKPAERHKDDSRGLVLPGYKYLGPFNGLDKGEPVNEADAAALEHDKAYDRQLDSGDNPYLKYNHADAEFQERLKEDTSFGGNLGRAVFQ
AAV2 ........................................................................................................................
130 140 150 160 170 180 190 200 210 220 230 240
7m8 AKKRVLEPLGLVEEPVKTAPGKKRPVEHSPVEPDSSSGTGKAGQQPARKRLNFGQTGDADSVPDPQPLGQPPAAPSGLGTNTMATGSGAPMADNNEGADGVGNSSGNWHCDSTWMGDRVT
AAV2 .......................................................................................................................I
250 260 270 280 290 300 310 320 330 340 350 360
7m8 TTSTRTWALPTYNNHLYKQISSQSGASNDNHYFGYSTPWGYFDFNRFHCHFSPRDWQRLINNNWGFRPKRLNFKLFNIQVKEVTQNDGTTTIANNLTSTVQVFTDSEYQLPYVLGSAHQG
AAV2 ........................................................................................................................
370 380 390 400 410 420 430 440 450 460 470 480
7m8 CLPPFPADVFMVPQYGYLTLNNGSQAVGRSSFYCLEYFPSQMLRTGNNFTFSYTFEDVPFHSSYAHSQSLDRLMNPLIDQYLYYLSRTNTPSGTTTQSRLQFSQAGASDIRDQSRNWLPG
AAV2 ........................................................................................................................
490 500 510 520 530 540 550 560 570 580 590 600
7m8 PCYRQQRVSKTSADNNNSEYSWTGATKYHLNGRDSLVNPGPAMASHKDDEEKFFPQSGVLIFGKQGSEKTNVDIEKVMITDEEEIRTTNPVATEQYGSVSTNLQRGNLALGETTRPARQA
AAV2 ...........................................................................................................----------...
610 620 630 640 650 660 670 680 690 700 710 720
7m8 ATADVNTQGVLPGMVWQDRDVYLQGPIWAKIPHTDGHFHPSPLMGGFGLKHPPPQILIKNTPVPANPSTTFSAAKFASFITQYSTGQVSVEIEWELQKENSKRWNPEIQYTSNYNKSINV
AAV2 .....................................................................................................................V..
730 740
7m8 DFTVDTNGVYSEPRPIGTRYLTRNL
AAV2 .........................
Parental composition of sequence LI-A
10 20 30 40 50 60 70 80 90 100 110 120
LI-A MAADGYLPDWLEDTLSEGIRQWWKLKPGPPPPKPAERHKDDSRGLVLPGYKYLGPFNGLDKGEPVNEADAAALEHDKAYDRQLDSGDNPYLKYNHADAEFQERLKEDTSFGGNLGRAVFQ
AAV2 ........................................................................................................................
130 140 150 160 170 180 190 200 210 220 230 240
LI-A AKKRVLEPLGLVEEPVKTAPGKKRPVEHSPVEPDSSSGTGKAGQQPARKRLNFGQTGDADSVPDPQPLGQPPAAPSGLGTNTMATGSGAPMADNNEGADGVGNSSGNWHCDSTWMGDRVI
AAV2 ........................................................................................................................
250 260 270 280 290 300 310 320 330 340 350 360
LI-A TTSTRTWALPTYNNHLYKQISSASGASNDNHYFGYSTPWGYFDFNRFHCHFSPRDWQRLINNNWGFRPKRLNFKLFNIQVKEVTQNDGTTTIANNLTSTVQVFTDSEYQLPYVLGSAHQG
AAV2 ......................Q.................................................................................................
370 380 390 400 410 420 430 440 450 460 470 480
LI-A CLPPFPADVFMVPQYGYLTLNNGSQAVGRSSFYCLEYFPSQMLRTGNNFTFSYTFEDVPFHSSYAHSQSLDRLMNPLIDQYLYFLSRTNSEGSLTTQSSLGFSQAGASDIRDQSRNWLPG
AAV2 ...................................................................................Y.....TPSGT....R.Q...................
490 500 510 520 530 540 550 560 570 580 590 600
LI-A PCYRQQRVSKTDGENNNSDFSWTGATKYHLNGRDSLVNPGPAMASHKDDEEKFFPQSGVLIFGKQGSEKTNVDIEKVMITDEEEIRTTNPVATEQYGSVSTNLQRGNRQAATADVNTQGV
AAV2 ...........SAD....EY....................................................................................................
610 620 630 640 650 660 670 680 690 700 710 720
LI-A LPGMVWQDRDVYLQGPIWAKIPHTDGHFHPSPLMGGFGLKHPPPQILIKNTPVPANPSTTFSAAKFASFITQYSTGQVSVEIEWELQKENSKRWNPEIQYTSNYNKSVNVDFTVDTNGVY
AAV2 ........................................................................................................................
730
LI-A SEPRPIGTRYLTRNL
AAV2 ...............
Parental composition of sequence LI-C
10 20 30 40 50 60 70 80 90 100 110 120
LI-C MAADGYLPDWLEDTLSEGIRQWWKLKPGPPPPKPAERHKDDSRGLVLPGYKYLGPFNGLDKGEPVNEADAAALEHDKAYDRQLDSGDNPYLKYNHADAEFQERLKEDTSFGGNLGRAVFQ
AAV2 ........................................................................................................................
130 140 150 160 170 180 190 200 210 220 230 240
LI-C AKKRVLEPLGLVEEPVKTAPGKKRPVEHSPVEPDSSSGTGKAGQQPARKRLNFGQTGDADSVPDPQPLGQPPAAPSGLGTNTMATGSGAPMADNNEGADGVGNSSGNWHCDSTWMGDRVI
AAV2 ........................................................................................................................
250 260 270 280 290 300 310 320 330 340 350 360
LI-C TTSTRTWALPTYNNHLYKQISSASGASNDNHYFGYSTPWGYFDFNRFHCHFSPRDWQRLINNNWGFRPKRLNFKLFNIQVKEVTQNDGTTTIANNLTSTVQVFTDSEYQLPYVLGSAHQG
AAV2 ......................Q.................................................................................................
370 380 390 400 410 420 430 440 450 460 470 480
LI-C CLPPFPADVFMVPQYGYLTLNNGSQAVGRSSFYCLEYFPSQMLRTGNNFTFSYTFEDVPFHSSYAHSQSLDRLMNPLIDQYLYYLSRTNTPSGTTTQSRLQFSQAGASDIRDQSRNWLPG
AAV2 ........................................................................................................................
490 500 510 520 530 540 550 560 570 580 590 600
LI-C PCYRQQRVSKTSADNNNSEFSWPGATTYHLNGRDSLVNPGPAMASHKDDEEKFFPQSGVLIFGKQGSEKTNVDIEKVMITDEEEIRTTNPVATEQYGSVSTNLQRGNRQAATADVNTQGV
AAV2 ...................Y..T...K.............................................................................................
610 620 630 640 650 660 670 680 690 700 710 720
LI-C LPGMVWQDRDVYLQGPIWAKIPHTDGHFHPSPLMGGFGLKHPPPQILIKNTPVPANPSTTFSAAKFASFITQYSTGQVSVEIEWELQKENSKRWNPEIQYTSNYNKSVNVDFTVDTNGVY
AAV2 ........................................................................................................................
730
LI-C SEPRPIGTRYLTRNL
AAV2 ...............
Parental composition of sequence NP84
10 20 30 40 50 60 70 80 90 100 110 120
NP84 MAADGYLPDWLEDTLSEGIRQWWKLKPGPPPPKPAERHKDDSRGLVLPGYKYLGPFNGLDKGEPVNEADAAALEHDKAYDRQLDSGDNPYLKYNHADAEFQERLKEDTSFGGNLGRAVFQ
AAV2 ........................................................................................................................
AAV3B
AAV6
130 140 150 160 170 180 190 200 210 220 230 240
NP84 AKKRVLEPLGLVEEPVKTAPGKKRPVEHSPVEPDSSSGTGKTGQQPAKKRLNFGQTGDSESVPDPQPLGEPPAAPSGLGTNTMATGSGAPMADNNEGADGVGNSSGNWHCDSQWLGDRVI
AAV2 ......................................... ..........................................
AAV3B .................................
AAV6 ..................................
250 260 270 280 290 300 310 320 330 340 350 360
NP84 TTSTRTWALPTYNNHLYKQISSQSGASNDNHYFGYSTPWGYFDFNRFHCHFSPRDWQRLINNNWGFRPKKLSFKLFNIQVKEVTQNDGTTTIANNLTSTVQVFTDSEYQLPYVLGSAHQG
AAV2 ................................................
AAV3B ........................................................................................................................
370 380 390 400 410 420 430 440 450 460 470 480
NP84 CLPPFPADVFMVPQYGYLTLNNGSQAVGRSSFYCLEYFPSQMLRTGNNFTFSYTFEDVPFHSSYAHSQSLDRLMNPLIDQYLYYLSRTNTPSGTTTQSRLQFSQAGASDIRDQSRNWLPG
AAV2 ........................................................................................................................
AAV3B .................................................
490 500 510 520 530 540 550 560 570 580 590 600
NP84 PCYRQQRVSKTSADNNNSEYSWTGATKYHLNGRDSLVNPGPAMASHKDDEEEFFPQSGVLIFGKQGSEKTNVDIEKVMITDEEEIRTTNPVATEQYGSVSTNLQGGNRQAATADVNTQGV
AAV2 ...................................................K....................................................R...............
610 620 630 640 650 660 670 680 690 700 710 720
NP84 LPGMVWQDRDVYLQGPIWAKIPHTDGHFHPSPLMGGFGLKHPPPQILIKNTPVPANPSTTFSAAKFASFITQYSTGQVSVEIEWELQKENSKRWNPEIQYTSNYNKSVNVDFTVDTNGVY
AAV2 ........................................................................................................................
730
NP84 SEPRPIGTRYLTRNL
AAV2 ...............
Parental composition of sequence OLIG001
10 20 30 40 50 60 70 80 90 100 110 120
OLIG001 MAADGYLPDWLEDTLSEGIRQWWKLKPGPPPPKPAERHKDDSRGLVLPGYKYLGPFNGLDKGEPVNEADAAALEHDKAYDRQLDSGDNPYLKYNHADAEFQERLKEDTSFGGNLGRAVFQ
AAV2 ........................................................................................................................
AAV6
AAV8
AAV9 ...................................
130 140 150 160 170 180 190 200 210 220 230 240
OLIG001 AKKRLLEPLGLVEEAAKTAPGKKRPVEQSPQEPDSSSGIGKTGQQPAKKRLNFGQTGDTESVPDPQPIGEPPAAPSGVGSLTMASGGGAPVADNNEGADGVGSSSGNWHCDSQWLGDRVI
AAV2 ....
AAV6 ...........................................
AAV8 .......
AAV9 .................................... ............................................................................
250 260 270 280 290 300 310 320 330 340 350 360
OLIG001 TTSTRTWALPTYNNHLYKQISNGTSGGATNDNTYFGYSTPWGYFDFNRFHCHFSPRDWQRLINNNWGFRPKRLSFKLFNIQVKEVTQNEGTKTIANNLTSTVQVFTDSEYQLPYVLGSAH
AAV2 ............................
AAV6
AAV8 ..................................................................................................... ..................
AAV9 ......................
370 380 390 400 410 420 430 440 450 460 470 480
OLIG001 QGCLPPFPADVFMIPQYGYLTLNNGSQAVGRSSFYCLEYFPSQMLRTGNNFQFTYTFEDVPFHSSYAHSQSLDRLMNPLIDQYLYYLSRTQTTGGTANTQTLGFSQGGPNTMANQAKNWL
AAV2 .............
AAV6
AAV8 ........................................................................................................................
490 500 510 520 530 540 550 560 570 580 590 600
OLIG001 PGPCYRQQRVSTTTGQNNNSNFAWTAGTKYHLNGRNSLANPGIAMATHKDDKERFFPSNGILIFGKQNAARDNADYSDVMLTSEEEIKTTNPVATEEYGIVADNLQQQNTAPQIGTVNSQ
AAV6
AAV8 ...................................................E....................................................................
610 620 630 640 650 660 670 680 690 700 710 720
OLIG001 GALPGMVWQNRDVYLQGPIWAKIPHTDGNFHPSPLMGGFGLKHPPPQILIKNTPVPADPPTTFNQSKLNSFITQYSTGQVSVEIEWELQKENSKRWNPEIQYTSNYYKSTSVDFAVNTEG
AAV6
AAV8 ........................................................................................................................
730
OLIG001 VYSEPHPIGTRYLTRPL
AAV6 ...........
AAV8 .....
Parental composition of sequence AAV2i8
10 20 30 40 50 60 70 80 90 100 110 120
AAV2i8 MAADGYLPDWLEDTLSEGIRQWWKLKPGPPPPKPAERHKDDSRGLVLPGYKYLGPFNGLDKGEPVNEADAAALEHDKAYDRQLDSGDNPYLKYNHADAEFQERLKEDTSFGGNLGRAVFQ
AAV2 ........................................................................................................................
AAV8
130 140 150 160 170 180 190 200 210 220 230 240
AAV2i8 AKKRVLEPLGLVEEPVKTAPGKKRPVEHSPVEPDSSSGTGKAGQQPARKRLNFGQTGDADSVPDPQPLGQPPAAPSGLGTNTMATGSGAPMADNNEGADGVGNSSGNWHCDSTWMGDRVI
AAV2 ........................................................................................................................
AAV8
250 260 270 280 290 300 310 320 330 340 350 360
AAV2i8 TTSTRTWALPTYNNHLYKQISSQSGASNDNHYFGYSTPWGYFDFNRFHCHFSPRDWQRLINNNWGFRPKRLNFKLFNIQVKEVTQNDGTTTIANNLTSTVQVFTDSEYQLPYVLGSAHQG
AAV2 ........................................................................................................................
AAV8
370 380 390 400 410 420 430 440 450 460 470 480
AAV2i8 CLPPFPADVFMVPQYGYLTLNNGSQAVGRSSFYCLEYFPSQMLRTGNNFTFSYTFEDVPFHSSYAHSQSLDRLMNPLIDQYLYYLSRTNTPSGTTTQSRLQFSQAGASDIRDQSRNWLPG
AAV2 ........................................................................................................................
AAV8
490 500 510 520 530 540 550 560 570 580 590 600
AAV2i8 PCYRQQRVSKTSADNNNSEYSWTGATKYHLNGRDSLVNPGPAMASHKDDEEKFFPQSGVLIFGKQGSEKTNVDIEKVMITDEEEIRTTNPVATEQYGSVSTNLQQQNTAPATADVNTQGV
AAV2 ........................................................................................................ ..........
AAV8 .........
610 620 630 640 650 660 670 680 690 700 710 720
AAV2i8 LPGMVWQDRDVYLQGPIWAKIPHTDGHFHPSPLMGGFGLKHPPPQILIKNTPVPANPSTTFSAAKFASFITQYSTGQVSVEIEWELQKENSKRWNPEIQYTSNYNKSVNVDFTVDTNGVY
AAV2 ........................................................................................................................
730
AAV2i8 SEPRPIGTRYLTRNL
AAV2 ...............
Parental composition of sequence rAAV2-retro
10 20 30 40 50 60 70 80 90 100 110 120
rAAV2-retro MAADGYLPDWLEDTLSEGIRQWWKLKPGPPPPKPAERHKDDSRGLVLPGYKYLGPFNGLDKGEPVNEADAAALEHDKAYDRQLDSGDNPYLKYNHADAEFQERLKEDTSFGGNLGRAVFQ
AAV2 ........................................................................................................................
130 140 150 160 170 180 190 200 210 220 230 240
rAAV2-retro AKKRVLEPLGLVEEPVKTAPGKKRPVEHSPVEPDSSSGTGKAGQQPARKRLNFGQTGDADSVPDPQPLGQPPAAPSGLGTNTMATGSGAPMADNNEGADGVGNSSGNWHCDSTWMGDRVI
AAV2 ........................................................................................................................
250 260 270 280 290 300 310 320 330 340 350 360
rAAV2-retro TTSTRTWALPTYNNHLYKQISSQSGASNDNHYFGYSTPWGYFDFNRFHCHFSPRDWQRLINNNWGFRPKRLNFKLFNIQVKEVTQNDGTTTIANNLTSTVQVFTDSEYQLPYVLGSAHQG
AAV2 ........................................................................................................................
370 380 390 400 410 420 430 440 450 460 470 480
rAAV2-retro CLPPFPADVFMVPQYGYLTLNDGSQAVGRSSFYCLEYFPSQMLRTGNNFTFSYTFEDVPFHSSYAHSQSLDRLMNPLIDQYLYYLSRTNTPSGTTTQSRLQFSQAGASDIRDQSRNWLPG
AAV2 .....................N..................................................................................................
490 500 510 520 530 540 550 560 570 580 590 600
rAAV2-retro PCYRQQRVSKTSADNNNSEYSWTGATKYHLNGRDSLVNPGPAMASHKDDEEKFFPQSGVLIFGKQGSEKTNVDIEKVMITDEEEIRTTNPVATEQYGSVSTNLQRGNLADQDYTKTARQA
AAV2 ...........................................................................................................----------...
610 620 630 640 650 660 670 680 690 700 710 720
rAAV2-retro ATADVNTQGVLPGMVWQDRDVYLQGPIWAKIPHTDGHFHPSPLMGGFGLKHPPPQILIKNTPVPANPSTTFSAAKFASFITQYSTGQVSVEIEWELQKENSKRWNPEIQYTSNYNKSINV
AAV2 .....................................................................................................................V..
730 740
rAAV2-retro DFTVDTNGVYSEPRPIGTRYLTRNL
AAV2 .........................
Parental composition of sequence AAV2-sept-Y-F
Sequence name too long, replaced with S14 (the number indicates sequence position in the variant file)
10 20 30 40 50 60 70 80 90 100 110 120
S14 MAADGYLPDWLEDTLSEGIRQWWKLKPGPPPPKPAERHKDDSRGLVLPGYKYLGPFNGLDKGEPVNEADAAALEHDKAYDRQLDSGDNPYLKYNHADAEFQERLKEDTSFGGNLGRAVFQ
AAV2 ........................................................................................................................
130 140 150 160 170 180 190 200 210 220 230 240
S14 AKKRVLEPLGLVEEPVKTAPGKKRPVEHSPVEPDSSSGTGKAGQQPARKRLNFGQTGDADSVPDPQPLGQPPAAPSGLGTNTMATGSGAPMADNNEGADGVGNSSGNWHCDSTWMGDRVI
AAV2 ........................................................................................................................
250 260 270 280 290 300 310 320 330 340 350 360
S14 TTSTRTWALPTFNNHLYKQISSQSGASNDNHFFGYSTPWGYFDFNRFHCHFSPRDWQRLINNNWGFRPKRLNFKLFNIQVKEVTQNDGTTTIANNLTSTVQVFTDSEYQLPYVLGSAHQG
AAV2 ...........Y...................Y........................................................................................
370 380 390 400 410 420 430 440 450 460 470 480
S14 CLPPFPADVFMVPQYGYLTLNNGSQAVGRSSFYCLEYFPSQMLRTGNNFTFSYTFEDVPFHSSYAHSQSLDRLMNPLIDQYLYFLSRTNTPSGTTTQSRLQFSQAGASDIRDQSRNWLPG
AAV2 ...................................................................................Y....................................
490 500 510 520 530 540 550 560 570 580 590 600
S14 PCYRQQRVSKTSADNNNSEFSWTGATKYHLNGRDSLVNPGPAMASHKDDEEKFFPQSGVLIFGKQGSEKTNVDIEKVMITDEEEIRTTNPVATEQYGSVSTNLQRGNRQAATADVNTQGV
AAV2 ...................Y....................................................................................................
610 620 630 640 650 660 670 680 690 700 710 720
S14 LPGMVWQDRDVYLQGPIWAKIPHTDGHFHPSPLMGGFGLKHPPPQILIKNTPVPANPSTTFSAAKFASFITQYSTGQVSVEIEWELQKENSKRWNPEIQFTSNFNKSVNVDFTVDTNGVY
AAV2 ...................................................................................................Y...Y................
730
S14 SEPRPIGTRFLTRNL
AAV2 .........Y.....