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Design spacer for CRISPR-Csm transcript targeting systems [feature request] #28

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abearab opened this issue Jul 21, 2023 · 2 comments
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enhancement New feature or request

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@abearab
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abearab commented Jul 21, 2023

Are you adding any features for CRISPR-Csm transcript targeting systems?

https://www.nature.com/articles/s41587-022-01649-9

@Jfortin1
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@abearab We haven't considered the CRISPR-Csm system, but it shouldn't be too hard to implement.
Do you have a specific use case in mind?

@abearab
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abearab commented Oct 10, 2023

@Jfortin1 Thanks for your attention. I was thinking about efficiently designing RNA targeting guide RNAs. For instance, here in Figure S8 there are m6A RNA modifications reported in specific loci and let's say I want to design an experiment to target that region using CRISPR-Csm system. What do you think?


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@Jfortin1 Jfortin1 self-assigned this Jan 16, 2024
@Jfortin1 Jfortin1 added the enhancement New feature or request label Jan 16, 2024
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