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DESCRIPTION
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DESCRIPTION
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Package: OneArmPhaseTwoStudy
Type: Package
Title: Planning, Conducting, and Analysing Single-Arm Phase II Studies
Version: 1.0.3
Date: 2017-11-13
Author: Marius Wirths
Maintainer: Johannes Krisam <[email protected]>
Description: Purpose of this package is it to plan, monitor and evaluate
oncological phase II studies. In general this kind of studies are single-arm
trials with planned interim analysis and binary endpoint. To meet the resulting
requirements, the package provides functions to calculate and evaluate 'Simon's
two-stage designs' and 'so-called' 'subset designs'. If you are unfamiliar with
this package a good starting point is to take a closer look at the functions
getSolutions() and getSolutionsSub1().The web-based tool (<https://imbi.shinyapps.io/phaseII-app/>)
extends the functionality of our R package by means of a proper dealing with over- and underrunning.
The R function binom.test of the 'stats' R package and the package 'binom' might be
helpful to assess the performance of the corresponding one-stage design as a reference.
License: GPL (>= 2)
Depends: methods, stats, Rcpp (>= 0.9.11), R (>= 3.1.0)
LinkingTo: Rcpp
RcppModules: simon, sub1
RoxygenNote: 6.0.1
NeedsCompilation: yes
Packaged: 2017-11-13 11:41:10 UTC; admin
Repository: CRAN
Date/Publication: 2017-11-13 11:54:38 UTC