This folder will contain the RNA blocks generated by the make_RNA_Blocks.py script.
For each Rfam seed alignment, we removed redundant primary sequences up to a specified threshold of identity (50%, 62%, and 90%), and considered the underlying alignments of secondary structures. Then, we converted the secondary structure in each of the structural encoding presented.
The make_RNA_Blocks.py script selects each column in the alignments to be part of the RNA Block of that family if
- no gaps were present, and
- a structural consensus, dependent on the chosen alphabet, exists (i.e. there must be a character with a relative frequency >50%).