error while running generate_ligands.py

[MachineGUN001]

hi, Arn,

thanks for your update on the repo.
but when I try to run generate_ligands.py, I get the following error:

File "d:\Cheminfo_Workshop\4_Fragment_Scaffold_Evolution\DiffSBDD-main\utils.py", line 69, in write_xyz_file
    with open(filename, 'w') as f:
PermissionError: [Errno 13] Permission denied: 'C:\\Users\\lsy\\AppData\\Local\\Temp\\tmp8oe6ibtz'

my OS system is windows10, python 3.8
this problem I have not seen before. and could you please provide some suggestions how to fix it u?

many thanks,

Best,

Sh-Y